OSF Healthcare Cancer Institute - Breakthrough Treatment Center
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Breakthrough news

3D microscopic illustration of immune cells attacking cancer cells, with antibodies binding to tumor cell surfaces in a vibrant cellular environment
Endometrial Cancer

OSF HealthCare Cancer Institute Participates in Phase 3 Research Study of Investigational B7-H4-Targeted Therapy for Advanced Endometrial Cancer
3D illustration of antibodies (blue Y-shaped structures) binding to an ovarian cancer cell or tumor mass, depicting targeted immunotherapy attacking cancer cells
Ovarian Cancer

OSF HealthCare Cancer Institute Participates in Phase 2 Research Study of Investigational Antibody-Drug Conjugate Combination for Newly Diagnosed Advanced-Stage Ovarian Cancer
3D illustration of PARP-1 Inhibitor
Phase 1 Relapsed Ovarian Cancer

OSF HealthCare Cancer Institute Begins Phase 1 Research Study of Investigational PARP1-Specific Inhibitor Combination for Relapsed Ovarian Cancer
alt="Composite image: architectural floor plan of the OSF Healthcare Cancer Institute showing 36 exam rooms, 4 theranostics rooms, treatment areas, waiting, seating, executive suite, and SPECT/CT boundary; paired with 3D molecular models of protein structures in white with orange and yellow binding highlights
Cancer Institute Acceleration

OSF HealthCare expanding OSF Cancer Institute
picture of an OSF Patient whose surgical plan and life was changed by 3D imaging technology
Surgical Advances

3D imaging technology changes surgical plan and life for OSF patient
3D illustration of a targeted antibody drug conjugate
SCLC ADC Phase 3 Study

OSF HealthCare Cancer Institute Begins Phase 3 Research Study of Investigational DLL3-Targeted Antibody-Drug Conjugate for Relapsed Small Cell Lung Cancer
3D molecular model of PARP-1 Inhibitor in orange and red straddling a blue helical membrane structure, illustrating a key receptor or signaling protein targeted in cancer therapies
Phase 1 SCLC Lung Cancer Study

OSF HealthCare Cancer Institute Opens Innovative Phase 1 Study for Relapsed Small Cell Lung Cancer
3D illustration of non-small cell lung cancer cells in blue and purple with green surface projections, clustered in a tumor microenvironment surrounded by normal tissue cells
Phase 1 Lung Cancer Study

OSF HealthCare Cancer Institute Opens Phase 1 Non-small Cell Lung Cancer Research Study
Composite image: professional portrait of a smiling man in a dark suit and tie; paired with 3D molecular visualization of a protein complex with blue helical backbone and colorful clustered domains in purple, blue, and teal
Darren Sigal, MD Joins OSF Cancer Institute’s Breakthrough Treatment Center
3D illustration of antibodies (blue Y-shaped structures) binding to and attacking a cervical cancer cell surrounded by healthy tissue cells
Cervical Cancer

OSF HealthCare Cancer Institute Participates in Phase 4 Research Study for Recurrent or Metastatic Cervical Cancer
alt="3D molecular model of immunotherapy with pink and purple surfaces, gray central domains, and yellow binding sites or ligands protruding from multiple subunits, illustrating a key structure in cancer research or targeted therapy
Phase 1 NSLC Lung Cancer Study

OSF HealthCare Cancer Institute Begins Phase 1 Research Study of Investigational Anchored Immunotherapy for Advanced Non-Small Cell Lung Cancer
alt="Composite image: professional portrait of a Dr. Jun Zhang in glasses and dark suit with patterned tie; paired with 3D visualization of a complex blue neural or molecular network with red-orange highlights, illustrating advanced research in oncology or neuroscience"
OSF HealthCare Cancer Institute Welcomes Dr. Jun Zhang as Vice President of Oncology Research
Bold orange graphic with large white text 'BEAT CANCER' in all caps, featuring logos and text for OSF HealthCare Cancer Institute and Cancer Center at Illinois below
BEAT Cancer

The Cancer Center at Illinois (CCIL) and the OSF HealthCare Cancer Institute (OSF) are joining forces on the Breakthrough Engineering and Advanced Treatment (BEAT) of Cancer Research Initiative
KBStrong & Glioblastoma

KBStrong and OSF are bringing transformational collaboration in the global fight against Glioblastoma home to our community
Portrait of Sister Dianne Marie McGrew, OSF (1966–2024), a smiling nun in brown habit and white coif, seated with hands folded, wearing glasses and a cross necklace, with tribute text overlay and OSF HealthCare logo
Honoring Sister Diane Marie

The Sister Diane Marie Gynecological Research Fund within the OSF Breakthrough Treatment at the OSF HealthCare Cancer Institute
Composite image: modern server room with rows of illuminated blue data racks representing high-performance computing; paired with a grid of colorful brain scan images showing axial slices with yellow, green, and red activity or metabolic heatmaps
Artificial Intelligence

OSF Breakthrough Treatment Center is working to use AI to detect brain conditions
3D illustration representing cancer early detection: a prominent cancer cell in orange surrounded by blood cells and a glowing DNA double helix, symbolizing the role of molecular and cellular changes in identifying cancer at its earliest stages
Lung Cancer Screening

OSF Breakthrough Treatment Center helps investigate a revolutionary blood test to improve lung cancer screening
3D molecular model of a large blue tumor or nucleosome-like structure densely covered with filamentous extensions and spherical subunits, representing a key assembly in chromatin or cancer-related molecular research
Pancreatic Breakthroughs

OSF engaged in pioneering NIH research for early detection of pancreatic cancer
3D illustration of invasive cancer cells in red-orange with long tentacle-like protrusions spreading across tissue, depicting tumor invasion and metastasis
Solid Tumors

Investigating biomarker-guided therapies for patients with solid tumors
Abstract circular data visualization with concentric rings of colorful rectangular bars in rainbow hues radiating from a dark center, representing genomic or molecular complexity in cancer research
Children's Breakthroughs

OSF helping build an international undiagnosed and rare disease platform for children
Clinician demonstrating the ProBeam 360° proton therapy gantry, a state-of-the-art radiation treatment machine with blue-lit ring, in a high-tech oncology suite
Proton Therapy

First proton therapy patient at OSF Cancer Institute
3D medical illustration of ovarian cancer: reddish tumor cluster with invasive protrusions growing on the ovary within the uterus and fallopian tube anatomy
Gynecologic Oncology

OSF selected to become a member of the Gynecologic Oncology Group (GOG)
Circular Circos plot visualizing polygenic risk scores: concentric rings of multicolored genomic segments with flowing connections in rainbow hues representing genetic associations and risk variant interactions across the genome
Multi-disease Early Detection

OSF Breakthrough Treatment Center investigating polygenic risk scores
3D illustration of immune cells with long branching extensions surrounding and interacting with a large central cancer cell in orange, depicting an immune response against a tumor
New Hope

OSF HealthCare Unveils Breakthrough Treatment Center: A new center to offer the most promising medical advances and trial options to cancer patients

OSF Healthcare Cancer Institute - Breakthrough Treatment Center

The OSF Breakthrough Treatment Center at the OSF HealthCare Cancer Institute provides individuals battling the most difficult to treat cancers access to the most promising medical breakthroughs, novel therapies, and clinical trials from around the world.

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OSF HealthCare Cancer Institute
OSF HealthCare Cancer Institute
1310 N Missouri Ave, Peoria, IL 61603

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